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	<title>Early &#8211; Book and Author News</title>
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		<title>‘A surfyte of cheese doth bringe payne’: Leeds University transcribes early book on cheese &#124; Cheese</title>
		<link>https://bookandauthornews.com/a-surfyte-of-cheese-doth-bringe-payne-leeds-university-transcribes-early-book-on-cheese-cheese-2/</link>
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		<dc:creator><![CDATA[Tony Ramos]]></dc:creator>
		<pubDate>Fri, 18 Apr 2025 20:38:45 +0000</pubDate>
				<category><![CDATA[Book and Literature News]]></category>
		<category><![CDATA[Book]]></category>
		<category><![CDATA[bringe]]></category>
		<category><![CDATA[cheese]]></category>
		<category><![CDATA[doth]]></category>
		<category><![CDATA[Early]]></category>
		<category><![CDATA[Leeds]]></category>
		<category><![CDATA[payne]]></category>
		<category><![CDATA[surfyte]]></category>
		<category><![CDATA[transcribes]]></category>
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					<description><![CDATA[<p>They are 450-year-old words of wisdom but they will ring true with anyone rooting around the fridge for late night comfort: “A surfyte of cheese doth bringe payne.” The warning for people to curb their enthusiasm is contained in the earliest-known book on cheese in English, a publication that academics say is both fascinating and [&#8230;]</p>
<p>The post <a rel="nofollow" href="https://bookandauthornews.com/a-surfyte-of-cheese-doth-bringe-payne-leeds-university-transcribes-early-book-on-cheese-cheese-2/">‘A surfyte of cheese doth bringe payne’: Leeds University transcribes early book on cheese | Cheese</a> appeared first on <a rel="nofollow" href="https://bookandauthornews.com">Book and Author News</a>.</p>
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<p class="dcr-16w5gq9">They are 450-year-old words of wisdom but they will ring true with anyone rooting around the fridge for late night comfort: “A surfyte of cheese doth bringe payne.”</p>
<p class="dcr-16w5gq9">The warning for people to curb their enthusiasm is contained in the earliest-known book on cheese in English, a publication that academics say is both fascinating and nauseating.</p>
<p class="dcr-16w5gq9">The <a href="https://www.theguardian.com/books/2023/sep/13/blessed-are-the-cheesemakers-university-of-leeds-acquires-oldest-surviving-book-about-british-cheese" data-link-name="in body link" target="_blank" rel="noopener">University of Leeds acquired it at auction</a> in 2023 and it has now been transcribed and made available for everyone to read on its website.</p>
<p class="dcr-16w5gq9">It includes a recommendation to use rancid cheese and bacon fat as a cure for gout: “Havinge his joynts full of knobbes or knottes, hit came in my minde to macerate that olde cheese with the decoction of fatte bacon, and to beate the same well in a mortar, and so to laye hit to his knotted joyntes, which done that man was greatly eased of the gowte.”</p>
<p class="dcr-16w5gq9">No one at Leeds is urging people today to attempt rubbing such a foul mixture into their own knobbed and knotted joints but Alex Bamji, associate professor of early modern history at the university, said she was struck by the book’s contemporary resonance.</p>
<p class="dcr-16w5gq9">She pointed to the passage: “He that will judge whether cheese be a convenyent foode for him, must consider the nature of the body, and the disposicion and temperamente of the cheese and both considered he shalbe hable to judge whether he is like to take harme be cheese or not.”</p>
<p class="dcr-16w5gq9">Bamji said: “The term ‘dairy intolerant’ might not have been used then, but there’s certainly an understanding here that cheese works better in some people’s bodies than others – although the author explains this through the system of the ‘humors’, and the idea that your body will be either hotter or colder and drier or more moist.”</p>
<p class="dcr-16w5gq9">The book, titled <a href="https://explore.library.leeds.ac.uk/special-collections-explore/750167" data-link-name="in body link" target="_blank" rel="noopener">A Pamflyt Compiled of Cheese, Contayninge the Differences, Nature, Qualities, and Goodness, of the Same</a> probably dates from the 1580s and was unpublished and unknown until it surfaced at auction. It is 112 pages and bound in vellum. Its writer is not known.</p>
<p class="dcr-16w5gq9">Bamji said it could be best described as a treatise. “It’s a substantial piece of work,” she said. “As with other treatises from this period, the writer has woven together ancient knowledge with their own learning and experience.</p>
<p class="dcr-16w5gq9">“It’s such a great fit with what we know about how people understood the role of diet in health in the period. <a href="https://www.theguardian.com/food" data-link-name="in body link" data-component="auto-linked-tag" target="_blank" rel="noopener">Food</a> was useful both to prevent and to respond to illness, and ordinary people had quite a complex understanding of that.”</p>
<p class="dcr-16w5gq9">The food historian Peter Brears said he thought the book was remarkable. “I’ve never seen anything like it,” he said. “It’s probably the first comprehensive academic study of a single foodstuff to be written in the English language.”</p>
<p class="dcr-16w5gq9">Other passages in the book include affirming what most people think today – that the end of a meal is the best time to eat cheese. “Cheese doth presse downe the meate to the botome of the stomake,” it reads.</p>
<p class="dcr-16w5gq9">A less useful tip is that dog’s milk “doth cause a woman to be delivered of her childe before tyme”.</p>
<p class="dcr-16w5gq9">The transcription was made by Ruth Bramley, part of a team of re-enactors at Kentwell Hall in Suffolk.</p>
<p class="dcr-16w5gq9">Readings from the book can be heard on a special edition of <a href="https://www.bbc.co.uk/sounds/play/m0029zfj" data-link-name="in body link" target="_blank" rel="noopener">Radio 4’s The Food Programme</a> which includes an attempt to replicate one of the Tudor recipes.</p>
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<p><br />
<br /><a href="https://www.theguardian.com/food/2025/apr/18/take-it-cheesy-the-fascinating-disgusting-world-of-dairy-curd-in-the-tudor-era" target="_blank" rel="noopener">Source link </a></p>
<p>The post <a rel="nofollow" href="https://bookandauthornews.com/a-surfyte-of-cheese-doth-bringe-payne-leeds-university-transcribes-early-book-on-cheese-cheese-2/">‘A surfyte of cheese doth bringe payne’: Leeds University transcribes early book on cheese | Cheese</a> appeared first on <a rel="nofollow" href="https://bookandauthornews.com">Book and Author News</a>.</p>
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		<title>Rare letter offers glimpse into Bram Stoker’s early thoughts on Dracula &#124; Bram Stoker</title>
		<link>https://bookandauthornews.com/rare-letter-offers-glimpse-into-bram-stokers-early-thoughts-on-dracula-bram-stoker/</link>
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		<dc:creator><![CDATA[Tony Ramos]]></dc:creator>
		<pubDate>Fri, 18 Apr 2025 06:22:13 +0000</pubDate>
				<category><![CDATA[Book and Literature News]]></category>
		<category><![CDATA[Bram]]></category>
		<category><![CDATA[Dracula]]></category>
		<category><![CDATA[Early]]></category>
		<category><![CDATA[glimpse]]></category>
		<category><![CDATA[letter]]></category>
		<category><![CDATA[offers]]></category>
		<category><![CDATA[rare]]></category>
		<category><![CDATA[Stoker]]></category>
		<category><![CDATA[Stokers]]></category>
		<category><![CDATA[thoughts]]></category>
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					<description><![CDATA[<p>He had just unleashed one of the most famed gothic horror books on the world, a blood-curdling classic that chilled readers and has inspired countless authors, film-makers and video game developers ever since. But a rare note that Bram Stoker wrote only weeks after Dracula was published in 1897 gives a glimpse into the playful [&#8230;]</p>
<p>The post <a rel="nofollow" href="https://bookandauthornews.com/rare-letter-offers-glimpse-into-bram-stokers-early-thoughts-on-dracula-bram-stoker/">Rare letter offers glimpse into Bram Stoker’s early thoughts on Dracula | Bram Stoker</a> appeared first on <a rel="nofollow" href="https://bookandauthornews.com">Book and Author News</a>.</p>
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<p class="dcr-16w5gq9">He had just unleashed one of the most famed gothic horror books on the world, a blood-curdling classic that chilled readers and has inspired countless authors, film-makers and video game developers ever since.</p>
<p class="dcr-16w5gq9">But a rare note that <a href="https://www.theguardian.com/books/bram-stoker" data-link-name="in body link" data-component="auto-linked-tag" target="_blank" rel="noopener">Bram Stoker</a> wrote only weeks after Dracula was published in 1897 gives a glimpse into the playful fun he must have had with the novel.</p>
<p class="dcr-16w5gq9">In the letter – addressed to an unidentified “Williams” – Stoker writes: “I send you Dracula &amp; have honoured myself by writing your name in it … Lord forgive me. I am quite shameless. Yours ever, Bram Stoker.”</p>
<figure id="60d3bfcb-2bba-4b0f-b02f-b688e4855983" data-spacefinder-role="thumbnail" data-spacefinder-type="model.dotcomrendering.pageElements.ImageBlockElement" class="dcr-13rnsx0"><figcaption data-spacefinder-role="inline" class="dcr-1tx6u99"><span class="dcr-1inf02i"><svg width="18" height="13" viewbox="0 0 18 13"><path d="M18 3.5v8l-1.5 1.5h-15l-1.5-1.5v-8l1.5-1.5h3.5l2-2h4l2 2h3.5l1.5 1.5zm-9 7.5c1.9 0 3.5-1.6 3.5-3.5s-1.6-3.5-3.5-3.5-3.5 1.6-3.5 3.5 1.6 3.5 3.5 3.5z"/></svg></span><span class="dcr-1qvd3m6">Bram Stoker.</span> Photograph: Alamy</figcaption></figure>
<p class="dcr-16w5gq9"><a href="https://www.baylissbooks.co.uk/collections/buy-rare-books/products/bram-stoker-autograph-letter-signed-mentioning-dracula-1897" data-link-name="in body link" target="_blank" rel="noopener">Oliver Bayliss, of Bayliss Rare Books in London,</a> who sold the letter, said the note was personal, informal and revealing. Stoker was better known for his reserved and professional tone in the few letters that have survived but this one suggested an awareness of his book’s gothic extravagance and, perhaps, a playful pride in its dark theatricality. Bayliss said letters by Stoker were rare and ones in which he mentioned Dracula by name virtually unheard of.</p>
<p class="dcr-16w5gq9">“Less than a handful are known to exist, and those are typically formal acknowledgments. By contrast, this letter is informal, insightful, and dated just weeks after the book’s publication, making it one of the earliest and most candid authorial commentaries on the now-legendary novel.</p>
<p class="dcr-16w5gq9">“This letter gives us something we’ve never really had before: Stoker’s own voice, responding to Dracula around the moment it entered the world – not as an icon of horror, but as a new, uncertain work.</p>
<p class="dcr-16w5gq9">“Stoker’s humorous aside, ‘Lord forgive me. I am quite shameless’ has the ring of an artist knowingly pushing the boundaries of the gothic and enjoying it. It’s theatrical, cheeky, and utterly authentic. That tone simply doesn’t appear in his other known correspondence on the subject.”</p>
<p class="dcr-16w5gq9">Bayliss said there was what could be another word – or just a squiggle – in the “shameless” sentence: “I struggled with that but from deep review and looking even with a magnifying glass, I think it is just a squiggle, a typo. However, it could be ‘now’ which makes the quote all the more potent.”</p>
<p class="dcr-16w5gq9">Bayliss, who sells to institutions and private collectors, said: “Given the extraordinary rarity of this letter, it will have strong appeal to both. There’s also crossover with film and pop culture collectors, especially those with an eye on iconic 20th-century monsters.</p>
<p class="dcr-16w5gq9">“I could also see investor interest. Dracula is one of the most sought-after first editions in rare book collecting, and a letter signed by Stoker, directly referencing the vampire and revealing his early thoughts on the novel, is essentially one in a billion. Rarer than seeing a vampire in daylight.”</p>
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<p class="dcr-16w5gq9">The letter came from a seller on the west coast of the US, who had acquired it from a private collection where it had been since the 1970s. The piece was sold to an as yet unnamed buyer on Wednesday for £15,000.</p>
<p class="dcr-16w5gq9">Bayliss said: “It’s rather special to bring the letter back to the city where Dracula was first published – and where the letter was, in all likelihood, written while Stoker was managing the Lyceum Theatre.”</p>
<p class="dcr-16w5gq9"><span data-dcr-style="bullet"/> This article was amended on 16 April 2025 to add information about the inclusion of a squiggle – or the word “now” – in Bram Stoker’s sentence about being shameless.</p>
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<br /><a href="https://www.theguardian.com/books/2025/apr/16/rare-letter-bram-stoker-early-thoughts-dracula" target="_blank" rel="noopener">Source link </a></p>
<p>The post <a rel="nofollow" href="https://bookandauthornews.com/rare-letter-offers-glimpse-into-bram-stokers-early-thoughts-on-dracula-bram-stoker/">Rare letter offers glimpse into Bram Stoker’s early thoughts on Dracula | Bram Stoker</a> appeared first on <a rel="nofollow" href="https://bookandauthornews.com">Book and Author News</a>.</p>
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		<title>Brain Connectivity Linked With Cognition in People With Early Psychosis</title>
		<link>https://bookandauthornews.com/brain-connectivity-linked-with-cognition-in-people-with-early-psychosis-2/</link>
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		<dc:creator><![CDATA[Tony Ramos]]></dc:creator>
		<pubDate>Sat, 22 Feb 2025 19:09:49 +0000</pubDate>
				<category><![CDATA[Book and Literature News]]></category>
		<category><![CDATA[Brain]]></category>
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		<category><![CDATA[Psychosis]]></category>
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					<description><![CDATA[<p>December 16, 2024 • Research Highlight People with psychotic disorders like schizophrenia frequently experience cognitive difficulties, including problems with attention, concentration, and memory. These cognitive difficulties are often early symptoms that appear before the onset of psychosis. In a study funded by the National Institute of Mental Health, researchers identified consistent links between brain connectivity [&#8230;]</p>
<p>The post <a rel="nofollow" href="https://bookandauthornews.com/brain-connectivity-linked-with-cognition-in-people-with-early-psychosis-2/">Brain Connectivity Linked With Cognition in People With Early Psychosis</a> appeared first on <a rel="nofollow" href="https://bookandauthornews.com">Book and Author News</a>.</p>
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  <time class="pagestamp_news_time" datetime="2024-12-16">December 16, 2024</time><br />
  • <span class="pagestamp_news_type">Research Highlight</span></p>
<p>People with psychotic disorders like schizophrenia frequently experience cognitive difficulties, including problems with attention, concentration, and memory. These cognitive difficulties are often early symptoms that appear before the <a href="https://www.nimh.nih.gov/health/publications/understanding-psychosis" data-entity-type="node" data-entity-uuid="8e8b1cad-ab1d-44b2-969f-7abf4707f51b" data-entity-substitution="canonical" target="_blank" rel="noopener">onset of psychosis</a>. In a study funded by the National Institute of Mental Health, researchers identified consistent links between brain connectivity and cognitive function in people with early stage psychosis and in people at high risk who later developed psychosis. This discovery could help researchers and clinicians better understand the factors that lead to psychosis, informing earlier intervention and improved treatments.</p>
<h2>What did the researchers look at in the study?</h2>
<p>Researchers <a href="https://www.vumc.org/psychiatry/person/heather-burrell-ward-md" target="_blank" rel="noopener">Heather Burrell Ward, M.D. <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a> (Vanderbilt University Medical Center), <a href="https://connects.catalyst.harvard.edu/Profiles/display/Person/865" target="_blank" rel="noopener">Roscoe Brady, Jr., M.D., Ph.D. <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a> (Beth Israel Deaconess Medical Center), <a href="https://www.mcleanhospital.org/profile/kathryn-lewandowski" target="_blank" rel="noopener">Kathryn Eve Lewandowski, Ph.D. <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a> (McLean Hospital), and colleagues examined data from two large multisite studies. The studies—the Human Connectome Project for Early Psychosis (HCP-EP) and the North American Prodrome Longitudinal Study 2 (NAPLS2)—include participants with early psychosis or at high risk for psychosis, as well as healthy participants with no known risk for psychosis.</p>
<p>The research team performed a comprehensive analysis of participants’ neural connections, or connectome, to identify robust associations between brain connectivity and attention. Attention was measured using an auditory task specifically developed to assess sustained attention in people with or at risk for psychotic disorders. The task gauges three aspects of attention: vigilance, memory, and ability to manage interference.</p>
<p>In total, the researchers analyzed data from 96 HCP-EP participants with early psychosis and 213 NAPLS2 participants at high risk for psychosis.</p>
<h2>What did the study find?</h2>
<p>Overall, participants with psychosis or an increased risk for psychosis performed worse on the attention task than their peers who were not at risk for psychosis.</p>
<p>Data from participants with early psychosis revealed associations between their brain connectivity and attention, in line with the researchers’ hypothesis. Specifically, lower connectivity between an area in the medial prefrontal cortex and a region in the somatomotor cortex was associated with worse performance on the attention task. The researchers found a similar connectivity-cognition association among participants who were at increased risk for—and eventually developed—psychosis.</p>
<p>Data from the two studies showed no connectivity-cognition associations for high-risk participants who did not develop psychosis or for participants who were not at risk for psychosis.</p>
<h2>What do the results mean?</h2>
<p>These consistent links between brain connectivity and cognition point to specific brain circuits that may contribute to cognitive difficulties in people with psychotic disorders, even before psychosis develops. However, these links do not provide evidence of a causal relationship. The researchers suggest that experimental studies using noninvasive brain stimulation techniques could help determine whether changes in these brain circuits directly impact cognitive performance. If so, these circuits may serve as specific targets for therapeutic intervention.</p>
<p>Ward, Brady, Lewandowski, and colleagues note that recruiting participants is a particular challenge in this area of research, requiring considerable time, effort, and resources. Only a small proportion of people who are at risk for psychosis ultimately develop psychosis, and at-risk participants are often hard to identify. According to the researchers, these findings underscore how valuable large multi-site studies like HCP-EP and NAPLS2 are to improving our understanding of the factors that predict and contribute to psychosis.</p>
<h2>Reference</h2>
<p>Ward, H. B., Beermann, A., Xie, J., Yildiz, G., Manzanarez Felix, K., Addington, J., Bearden, C. E., Cadenhead, K., Cannon, T. D., Cornblatt, B., Keshavan, M., Mathalon, D., Perkins, D. O., Seidman, L., Stone, W. S., Tsuang, M. T., Walker, E. F., Woods, S., Coleman, M. J.,…Brady, R. O., Jr. (2024). Robust brain correlates of cognitive performance in psychosis and its prodrome. <em>Biological Psychiatry</em>, <em>97</em>(2), 139–147. <a href="https://doi.org/10.1016/j.biopsych.2024.07.012" target="_blank" rel="noopener">https://doi.org/10.1016/j.biopsych.2024.07.012 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a></p>
<h2>Grants</h2>
<p><a href="https://reporter.nih.gov/search/UpW6Bs_yoECV_QgTamMp7Q/project-details/7185159" target="_blank" rel="noopener">MH066134 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/FaOz2heFNU-wCxdSggPRXA/project-details/8705584" target="_blank" rel="noopener">MH066286 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/NfmMMvMfDUqcC1To_rcz1w/project-details/10125633" target="_blank" rel="noopener">MH120588-01A1 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/R_IBRmnwl0yvMlYlY6nK8g/project-details/9533695" target="_blank" rel="noopener">MH081902 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/jGdKhxMgk0-iP9oZ468Oww/project-details/9535480" target="_blank" rel="noopener">MH081857 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/dZH7iunJXE2Jvh1U1-KPbw/project-details/10560521" target="_blank" rel="noopener">MH117012 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/zKayfGXBLEi84jh_x248zQ/project-details/9655380" target="_blank" rel="noopener">MH109977 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/CHBg27l72UWE2MG1gN7lyQ/project-details/9515969" target="_blank" rel="noopener">MH082022 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/HNFv0CIspkikIrv1Oc3E9A/project-details/9515965" target="_blank" rel="noopener">MH081944 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/HFlE2aCwVEy5_a2R0TMR2A/project-details/7187395" target="_blank" rel="noopener">MH066069 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/KPm4CHbqzkCOOe13f2W41g/project-details/9520417" target="_blank" rel="noopener">MH076989 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/xV1dQyGELEKOuP0MYHG9sw/project-details/9533696" target="_blank" rel="noopener">MH081928 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/bYwm8_wG1EahT8z8esSq7A/project-details/9527185" target="_blank" rel="noopener">MH081988 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/gsE7GuarkUaCOrunzfLCTg/project-details/10527321" target="_blank" rel="noopener">MH116170 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a></p>
</p></div>
<p><br />
<br /><a href="https://www.nimh.nih.gov/news/science-updates/2024/brain-connectivity-linked-with-cognition-in-people-with-early-psychosis?utm_source=rss_readers&#038;utm_medium=rss&#038;utm_campaign=rss_summary" target="_blank" rel="noopener">Source link </a></p>
<p>The post <a rel="nofollow" href="https://bookandauthornews.com/brain-connectivity-linked-with-cognition-in-people-with-early-psychosis-2/">Brain Connectivity Linked With Cognition in People With Early Psychosis</a> appeared first on <a rel="nofollow" href="https://bookandauthornews.com">Book and Author News</a>.</p>
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		<title>Brain Connectivity Linked With Cognition in People With Early Psychosis</title>
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		<dc:creator><![CDATA[Tony Ramos]]></dc:creator>
		<pubDate>Sun, 12 Jan 2025 16:02:08 +0000</pubDate>
				<category><![CDATA[Book and Literature News]]></category>
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		<category><![CDATA[Cognition]]></category>
		<category><![CDATA[Connectivity]]></category>
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					<description><![CDATA[<p>December 16, 2024 • Research Highlight People with psychotic disorders like schizophrenia frequently experience cognitive difficulties, including problems with attention, concentration, and memory. These cognitive difficulties are often early symptoms that appear before the onset of psychosis. In a study funded by the National Institute of Mental Health, researchers identified consistent links between brain connectivity [&#8230;]</p>
<p>The post <a rel="nofollow" href="https://bookandauthornews.com/brain-connectivity-linked-with-cognition-in-people-with-early-psychosis/">Brain Connectivity Linked With Cognition in People With Early Psychosis</a> appeared first on <a rel="nofollow" href="https://bookandauthornews.com">Book and Author News</a>.</p>
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										<content:encoded><![CDATA[<p> <br />
</p>
<div id="main_content_inner">
<p class="pagestamp_news_wrap">
  <time class="pagestamp_news_time" datetime="2024-12-16">December 16, 2024</time><br />
  • <span class="pagestamp_news_type">Research Highlight</span></p>
<p>People with psychotic disorders like schizophrenia frequently experience cognitive difficulties, including problems with attention, concentration, and memory. These cognitive difficulties are often early symptoms that appear before the <a href="https://www.nimh.nih.gov/health/publications/understanding-psychosis" data-entity-type="node" data-entity-uuid="8e8b1cad-ab1d-44b2-969f-7abf4707f51b" data-entity-substitution="canonical" target="_blank" rel="noopener">onset of psychosis</a>. In a study funded by the National Institute of Mental Health, researchers identified consistent links between brain connectivity and cognitive function in people with early stage psychosis and in people at high risk who later developed psychosis. This discovery could help researchers and clinicians better understand the factors that lead to psychosis, informing earlier intervention and improved treatments.</p>
<h2>What did the researchers look at in the study?</h2>
<p>Researchers <a href="https://www.vumc.org/psychiatry/person/heather-burrell-ward-md" target="_blank" rel="noopener">Heather Burrell Ward, M.D. <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a> (Vanderbilt University Medical Center), <a href="https://connects.catalyst.harvard.edu/Profiles/display/Person/865" target="_blank" rel="noopener">Roscoe Brady, Jr., M.D., Ph.D. <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a> (Beth Israel Deaconess Medical Center), <a href="https://www.mcleanhospital.org/profile/kathryn-lewandowski" target="_blank" rel="noopener">Kathryn Eve Lewandowski, Ph.D. <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a> (McLean Hospital), and colleagues examined data from two large multisite studies. The studies—the Human Connectome Project for Early Psychosis (HCP-EP) and the North American Prodrome Longitudinal Study 2 (NAPLS2)—include participants with early psychosis or at high risk for psychosis, as well as healthy participants with no known risk for psychosis.</p>
<p>The research team performed a comprehensive analysis of participants’ neural connections, or connectome, to identify robust associations between brain connectivity and attention. Attention was measured using an auditory task specifically developed to assess sustained attention in people with or at risk for psychotic disorders. The task gauges three aspects of attention: vigilance, memory, and ability to manage interference.</p>
<p>In total, the researchers analyzed data from 96 HCP-EP participants with early psychosis and 213 NAPLS2 participants at high risk for psychosis.</p>
<h2>What did the study find?</h2>
<p>Overall, participants with psychosis or an increased risk for psychosis performed worse on the attention task than their peers who were not at risk for psychosis.</p>
<p>Data from participants with early psychosis revealed associations between their brain connectivity and attention, in line with the researchers’ hypothesis. Specifically, lower connectivity between an area in the medial prefrontal cortex and a region in the somatomotor cortex was associated with worse performance on the attention task. The researchers found a similar connectivity-cognition association among participants who were at increased risk for—and eventually developed—psychosis.</p>
<p>Data from the two studies showed no connectivity-cognition associations for high-risk participants who did not develop psychosis or for participants who were not at risk for psychosis.</p>
<h2>What do the results mean?</h2>
<p>These consistent links between brain connectivity and cognition point to specific brain circuits that may contribute to cognitive difficulties in people with psychotic disorders, even before psychosis develops. However, these links do not provide evidence of a causal relationship. The researchers suggest that experimental studies using noninvasive brain stimulation techniques could help determine whether changes in these brain circuits directly impact cognitive performance. If so, these circuits may serve as specific targets for therapeutic intervention.</p>
<p>Ward, Brady, Lewandowski, and colleagues note that recruiting participants is a particular challenge in this area of research, requiring considerable time, effort, and resources. Only a small proportion of people who are at risk for psychosis ultimately develop psychosis, and at-risk participants are often hard to identify. According to the researchers, these findings underscore how valuable large multi-site studies like HCP-EP and NAPLS2 are to improving our understanding of the factors that predict and contribute to psychosis.</p>
<h2>Reference</h2>
<p>Ward, H. B., Beermann, A., Xie, J., Yildiz, G., Manzanarez Felix, K., Addington, J., Bearden, C. E., Cadenhead, K., Cannon, T. D., Cornblatt, B., Keshavan, M., Mathalon, D., Perkins, D. O., Seidman, L., Stone, W. S., Tsuang, M. T., Walker, E. F., Woods, S., Coleman, M. J.,…Brady, R. O., Jr. (2024). Robust brain correlates of cognitive performance in psychosis and its prodrome. <em>Biological Psychiatry</em>, <em>97</em>(2), 139–147. <a href="https://doi.org/10.1016/j.biopsych.2024.07.012" target="_blank" rel="noopener">https://doi.org/10.1016/j.biopsych.2024.07.012 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a></p>
<h2>Grants</h2>
<p><a href="https://reporter.nih.gov/search/UpW6Bs_yoECV_QgTamMp7Q/project-details/7185159" target="_blank" rel="noopener">MH066134 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/FaOz2heFNU-wCxdSggPRXA/project-details/8705584" target="_blank" rel="noopener">MH066286 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/NfmMMvMfDUqcC1To_rcz1w/project-details/10125633" target="_blank" rel="noopener">MH120588-01A1 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/R_IBRmnwl0yvMlYlY6nK8g/project-details/9533695" target="_blank" rel="noopener">MH081902 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/jGdKhxMgk0-iP9oZ468Oww/project-details/9535480" target="_blank" rel="noopener">MH081857 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/dZH7iunJXE2Jvh1U1-KPbw/project-details/10560521" target="_blank" rel="noopener">MH117012 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/zKayfGXBLEi84jh_x248zQ/project-details/9655380" target="_blank" rel="noopener">MH109977 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/CHBg27l72UWE2MG1gN7lyQ/project-details/9515969" target="_blank" rel="noopener">MH082022 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/HNFv0CIspkikIrv1Oc3E9A/project-details/9515965" target="_blank" rel="noopener">MH081944 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/HFlE2aCwVEy5_a2R0TMR2A/project-details/7187395" target="_blank" rel="noopener">MH066069 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/KPm4CHbqzkCOOe13f2W41g/project-details/9520417" target="_blank" rel="noopener">MH076989 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/xV1dQyGELEKOuP0MYHG9sw/project-details/9533696" target="_blank" rel="noopener">MH081928 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/bYwm8_wG1EahT8z8esSq7A/project-details/9527185" target="_blank" rel="noopener">MH081988 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/gsE7GuarkUaCOrunzfLCTg/project-details/10527321" target="_blank" rel="noopener">MH116170 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a></p>
</p></div>
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<br /><a href="https://www.nimh.nih.gov/news/science-news/brain-connectivity-linked-with-cognition-in-people-with-early-psychosis?utm_source=rss_readers&#038;utm_medium=rss&#038;utm_campaign=rss_summary" target="_blank" rel="noopener">Source link </a></p>
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		<title>Haruki Murakami on Rethinking Early Work</title>
		<link>https://bookandauthornews.com/haruki-murakami-on-rethinking-early-work/</link>
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		<dc:creator><![CDATA[Tony Ramos]]></dc:creator>
		<pubDate>Sat, 16 Nov 2024 07:06:58 +0000</pubDate>
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					<description><![CDATA[<p>Haruki Murakami’s new novel, “The City and Its Uncertain Walls,” is also a return to earlier works: a novella he published in Japan, in 1980, when he was thirty-one, and the novel “Hard-Boiled Wonderland and the End of the World,” published five years later, which was, in part, an attempt to rethink that novella. In [&#8230;]</p>
<p>The post <a rel="nofollow" href="https://bookandauthornews.com/haruki-murakami-on-rethinking-early-work/">Haruki Murakami on Rethinking Early Work</a> appeared first on <a rel="nofollow" href="https://bookandauthornews.com">Book and Author News</a>.</p>
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<p class="has-dropcap has-dropcap__lead-standard-heading">Haruki Murakami’s new novel, “<a data-offer-url="https://www.amazon.com/City-Its-Uncertain-Walls-Novel/dp/0593801970" class="external-link" data-event-click="{&quot;element&quot;:&quot;ExternalLink&quot;,&quot;outgoingURL&quot;:&quot;https://www.amazon.com/City-Its-Uncertain-Walls-Novel/dp/0593801970&quot;}" href="https://www.amazon.com/City-Its-Uncertain-Walls-Novel/dp/0593801970" rel="nofollow noopener" target="_blank">The City and Its Uncertain Walls</a>,” is also a return to earlier works: a novella he published in Japan, in 1980, when he was thirty-one, and the novel “<a data-offer-url="https://www.amazon.com/Hardboiled-Wonderland-World-Haruki-Murakami/dp/0099448785" class="external-link" data-event-click="{&quot;element&quot;:&quot;ExternalLink&quot;,&quot;outgoingURL&quot;:&quot;https://www.amazon.com/Hardboiled-Wonderland-World-Haruki-Murakami/dp/0099448785&quot;}" href="https://www.amazon.com/Hardboiled-Wonderland-World-Haruki-Murakami/dp/0099448785" rel="nofollow noopener" target="_blank">Hard-Boiled Wonderland and the End of the World</a>,” published five years later, which was, in part, an attempt to rethink that novella. In the early days of the <em class="small">Covid</em> pandemic, feeling that, after forty more years of writing fiction, he finally had the dexterity and the time to return to this idea—of a high-walled town where clocks have no hands, people have banished their shadows, and a man works in a library “reading” old dreams—Murakami embarked on a larger portrait both of this surreal, almost mythical world and of the so-called real world. The result is a narrative full of twists and shifts, with an ending that purposely leaves us with questions to consider, among them, Which is the real world and which the shadow realm? Which is a physical landscape and which is psychological? How many lives does one person lead? How powerful can the imagination be?</p>
<p class="paywall">We discussed “The City and Its Uncertain Walls” and other things, via e-mail, in October. Murakami’s answers, which, like the novel, were translated, from the Japanese, by Philip Gabriel, have been lightly edited for clarity.</p>
<p class="paywall"><strong>Hi, Haruki. Congratulations on your new novel, “The City and Its Uncertain Walls,” which, as you write in the afterword, began in 1980 as a novella that was published in a Japanese literary magazine. What inspired the original novella?</strong></p>
<p class="paywall">It was a long time ago and I can’t really recall, but probably the world described there is a kind of enduring, essential landscape for me. I think I had the conviction then that it was a world I <em>had to write about</em>. The thing is, though, back then I lacked the writing skills I needed to do it justice.</p>
<p class="paywall"><strong>After publishing the novella, you felt unhappy with it, and you didn’t allow it to be published in book form or translated into other languages. What made you want to go back to it forty years later?</strong></p>
<p class="paywall">I wasn’t satisfied with the original novella I wrote. And that <em>dissatisfaction</em> stuck in my throat like a small fish bone, a sort of loose end for me as a writer. Somehow I wanted to resurrect that world in a more striking form—that was my long-held desire.</p>
<p class="paywall">Meanwhile, though, I became busy with all kinds of other projects I wanted to do and couldn’t get started on rewriting it. And some forty years passed (in the blink of an eye, it seemed). I’m in my seventies now, and I thought I really needed to get going on this rewriting of the novella, since I might not have all that much time left. I also had a strong, personal sense of wanting to fulfill my responsibility as a novelist.</p>
<p class="paywall"><strong>Some of the elements in “The City and Its Uncertain Walls” also appeared in your novel “Hard-Boiled Wonderland and the End of the World.” Was that book a first attempt at rewriting the original novella?</strong></p>
<p class="paywall">Exactly. That novel was my first attempt at a rewrite. “Hard-Boiled Wonderland and the End of the World” was a notable work as far as my writing career was concerned, and quite a few readers say it’s their favorite of my books, but when I look back now I feel that the timing was off, that it was too soon then to do a rewrite of the earlier novella. I was still young, and my storytelling stance tended to be a bit impulsive. As the years went by, I understood that I wanted to make it a calmer, quieter type of story.</p>
<p class="paywall"><strong>In “The City and Its Uncertain Walls,” there are two spaces in which the narrator spends time: one that we would call the real world, and another place, a town where no one has a shadow, unicorns flock, and the town walls mutate in order to keep people in. We can intuit metaphorical explanations for the town: it could be an embodiment of the narrator’s imagination or a kind of limbo between the corporeal world and the spirit world; it could be that we all exist in both places, without knowing it, and so on. Do you, as its creator, have specific ideas about the town’s identity and what it represents?</strong></p>
<p class="paywall">The town surrounded by walls was also a metaphor for the worldwide pandemic lockdown. How is it possible for both extreme isolation and warm feelings of empathy to coexist? That became one of the major themes of this novel.</p>
<p class="paywall"><strong>In the book, the narrator first hears about this other place, as a seventeen-year-old, from the girl he’s in love with. She feels that her “real” self is there, and that the girl the narrator knows is just a shadow. But the life that the narrator eventually leads in the walled town seems far more of a shadow life—gray, unchanging, dimly lit. Why would shadows inhabit the “real world” and the people they belong to inhabit a dark space outside of time?</strong></p>
<p class="paywall">Where do our <em>real selves</em> exist? Where does their meaning lie? What kind of place is the <em>real world</em>, anyway? Do we have any choices there? These are fundamental questions, and major themes of my novels.</p>
<p class="paywall"><strong>“The City and Its Uncertain Walls” reaches its end, but, as in much of your work, its fundamental mysteries are not solved or explained. Do you like to leave the reader with questions?</strong></p>
<p class="paywall">Basically, I think an outstanding novel will always aim to present compelling questions—but not give a clear-cut, easy-to-follow conclusion. I’d like my readers to have something to ponder after they’ve finished my books. To have them think, for instance, What endings would be possible here? I drop hints inside each story in order to leave readers thinking. What I’d like is for them to pick up on these hints and each arrive at their own, unique ending. Countless readers have written to me to say, I’ve enjoyed rereading the same book of yours so many times. As an author, nothing could please me more.</p>
<p class="paywall"><strong>If you, like your narrator, had to decide which of the two worlds you would want to stay in—the larger world we all know, or the city within those high walls—what would your choice be?</strong></p>
<p class="paywall">That question itself is the most important theme of this novel. Which would you choose? And do we even have a choice to begin with?</p>
<p class="paywall"><strong>There are some classic stories about shadows that separate from their original humans. In Hans Christian Andersen’s “</strong><a data-offer-url="https://www.amazon.com/Shadow-Hans-Christian-Andersen/dp/1480019291" class="external-link" data-event-click="{&quot;element&quot;:&quot;ExternalLink&quot;,&quot;outgoingURL&quot;:&quot;https://www.amazon.com/Shadow-Hans-Christian-Andersen/dp/1480019291&quot;}" href="https://www.amazon.com/Shadow-Hans-Christian-Andersen/dp/1480019291" rel="nofollow noopener" target="_blank"><strong>The Shadow</strong></a><strong>,” a man’s shadow separates from him, then enslaves and eventually kills him. Were you inspired by any other narratives?</strong></p>
<p class="paywall">I first read Hans Christian Andersen’s “The Shadow” only after I wrote the original novella, so that wasn’t the inspiration for it, though it is a fascinating story. The work I personally like that deals with shadows and doppelgängers is Edgar Allan Poe’s “William Wilson.”</p>
<p class="paywall"><strong>Did going back to a work you wrote more than forty years ago make you see the ways in which you’ve changed as a writer since then? Do you think you’ve changed?</strong></p>
<p class="paywall">I’ve changed quite a lot as a writer over these past forty years. When I was young, there were many times I’d want to write about something only to realize, sadly, that I wasn’t proficient enough to do so. As I’ve gained more experience, though, I’ve learned a lot, and with my skill set now as a writer I feel I can handle almost anything I want to write about. And, of course, that makes me very happy as a writer.</p>
<p class="paywall">Have I likewise changed a lot as a person? That’s a tough question, and the more I think about it the less I can say conclusively. Rewriting this work has certainly got me thinking more deeply, though, about that question.</p>
<p class="paywall"><strong>You recently translated Truman Capote into Japanese. Do you feel that the translating you do has an effect on your own writing?</strong></p>
<p class="paywall">Of course. The work of translating has taught me many things as a writer. Translation is <em>extreme close reading</em>, and is useful training to help you refine your own writing style. It’s also important, and meaningful, to try to <em>walk in someone else’s shoes</em>. And to continue to show respect to so many outstanding writers.</p>
<p class="paywall"><strong>Are there ways in which you’d still like to change?</strong></p>
<p class="paywall">There’s no particular thing that makes me think, <em>This</em> is what I’d like to change. It’s probably best for these changes to occur on their own as I write. I suppose you could put it the other way around and say that the reason I keep on writing novels, without growing tired of it, is to spur these changes in me to take place naturally.</p>
<p class="paywall"><strong>The past few years have been marked by wars around the world: between Russia and Ukraine, Israel and Hamas and Hezbollah, civil wars in Yemen, Sudan, Myanmar. There are currently more armed conflicts than there have been since the Second World War. Does this affect your approach to writing in any way? Do you feel a need to address global conflicts through fiction?</strong></p>
<p class="paywall">I feel like the pandemic was a turning point, and the world is in retreat now, being dragged back into the past. I might even go so far as to suggest that it’s becoming more <em>medievalized</em>. Globalism is in flight in a big way, with social media, once so promising, now reaching a dead end. The image of a town surrounded by high walls may reflect that situation, of things being blocked, and obstructed.</p>
<p class="paywall">Perhaps in this era we live in, older stories may reveal a kind of unexpected resonance. I’m really hopeful about that possibility.</p>
<p class="paywall"><strong>Are you working on a new book?</strong></p>
<p class="paywall">I keep my plans secret. ♦</p>
</div>
<p><br />
<br /><a href="https://www.newyorker.com/books/page-turner/haruki-murakami-on-rethinking-early-work" target="_blank" rel="noopener">Source link </a></p>
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		<title>Early version of Lord of the Flies with different beginning to go on display &#124; William Golding</title>
		<link>https://bookandauthornews.com/early-version-of-lord-of-the-flies-with-different-beginning-to-go-on-display-william-golding/</link>
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		<dc:creator><![CDATA[Tony Ramos]]></dc:creator>
		<pubDate>Mon, 16 Sep 2024 05:50:29 +0000</pubDate>
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					<description><![CDATA[<p>Lord of the Flies, the story of a group of British boys who are stranded on an uninhabited island and their disastrous attempts to govern themselves, is considered to be one of the greatest works of literary history, taught to schoolchildren around the world. But the novel by Sir William Golding didn’t always begin with [&#8230;]</p>
<p>The post <a rel="nofollow" href="https://bookandauthornews.com/early-version-of-lord-of-the-flies-with-different-beginning-to-go-on-display-william-golding/">Early version of Lord of the Flies with different beginning to go on display | William Golding</a> appeared first on <a rel="nofollow" href="https://bookandauthornews.com">Book and Author News</a>.</p>
]]></description>
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<div>
<p class="dcr-106f06m">Lord of the Flies, the story of a group of British boys who are stranded on an uninhabited island and their disastrous attempts to govern themselves, is considered to be one of the greatest works of literary history, taught to schoolchildren around the world.</p>
<p class="dcr-106f06m">But the novel by Sir <a href="https://www.theguardian.com/books/williamgolding" data-link-name="in body link" data-component="auto-linked-tag" target="_blank" rel="noopener">William Golding</a> didn’t always begin with the schoolboys crash-landing on the island. Instead, an original version of the manuscript, which was written in a school exercise book with the cover torn off, describes how they had been evacuated out, in the midst of a nuclear war, and their plane shot down in an aerial battle.</p>
<p class="dcr-106f06m">The alternative version of the dark societal tale will now go on display to celebrate the 70th anniversary of the book being published.</p>
<p class="dcr-106f06m">Golding’s manuscripts, notebooks and letters will also be shown in the exhibition at the Bill Douglas Cinema Museum, Old Library, University of Exeter later this month.</p>
<p class="dcr-106f06m">The original manuscript will not be on public view, due to its fragility, the university said. Golding’s daughter, Judy Carver, said: “The Golding family are grateful to the University of Exeter for their care of the manuscripts and typescripts on loan to the university.</p>
<p class="dcr-106f06m">“They also welcome this opportunity for these materials to be viewed by a wider audience. They appreciate the careful work that has brought the exhibition contents to public view.”</p>
<p class="dcr-106f06m">Golding, who died in 1993 at his home in Cornwall, was a Nobel prize-winning author. But he had difficulties getting Lord of the Flies taken up by publishers.</p>
<p class="dcr-106f06m">It was spotted by a junior editor at publishers Faber and Faber after a string of rejections, and after some changes became an overnight sensation in 1954.</p>
<p class="dcr-106f06m">The exhibit will also contain letters to the editor who helped him make Lord of the Flies a success, along with correspondence from Golding on his other novels and works.</p>
<p class="dcr-106f06m">Caroline Walter, the interim head of heritage collections at the University of Exeter, said: “This is an exciting opportunity to unite archival material from two distinct collections in Exeter, allowing visitors to delve into the rich literary heritage of the south-west and illuminating Golding’s creative journey.”</p>
<p class="dcr-106f06m">Golding went on to write The Inheritors, Pincher Martin and Free Fall along with Rites of Passage, which won him the Booker Prize.</p>
<p class="dcr-106f06m">There were film adaptations of his first novel in 1963 and 1990, and a new version is to be shown on TV for the first time by the BBC.</p>
<p class="dcr-106f06m">Written by <a href="https://www.theguardian.com/media/2016/apr/05/jack-thorne-philip-pullman-his-dark-materials-bbc" data-link-name="in body link" target="_blank" rel="noopener">His Dark Materials’ Jack Thorne</a>, the drama is being filmed in Malaysia with a young cast and will remain faithful to the original story of savagery and dark human nature.</p>
<p class="dcr-106f06m">The exhibition will be on display from 24 September to 15 December.</p>
<p class="dcr-106f06m">Display panels featuring information about Golding’s papers will be on show across Exeter from 2 September to 31 October and there will be free public events in the city this autumn.</p>
</div>
<p><br />
<br /><a href="https://www.theguardian.com/books/2024/sep/12/lord-of-the-flies-alternate-original-beginning-nuclear-war-exhibition" target="_blank" rel="noopener">Source link </a></p>
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		<title>Digital Autism Screening Tool Could Enhance Early Identification</title>
		<link>https://bookandauthornews.com/digital-autism-screening-tool-could-enhance-early-identification/</link>
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		<dc:creator><![CDATA[Tony Ramos]]></dc:creator>
		<pubDate>Wed, 19 Jun 2024 13:11:56 +0000</pubDate>
				<category><![CDATA[Book and Literature News]]></category>
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					<description><![CDATA[<p>June 13, 2024 • Research Highlight A tablet-based screening tool that analyzes children’s behavior in response to specific video clips shows promise for enhancing early autism screening, according to a study supported in part by the National Institute of Mental Health. While early autism screening typically depends on parent questionnaires, data suggest the accuracy of [&#8230;]</p>
<p>The post <a rel="nofollow" href="https://bookandauthornews.com/digital-autism-screening-tool-could-enhance-early-identification/">Digital Autism Screening Tool Could Enhance Early Identification</a> appeared first on <a rel="nofollow" href="https://bookandauthornews.com">Book and Author News</a>.</p>
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  <time class="pagestamp_news_time" datetime="2024-06-13">June 13, 2024</time><br />
  • <span class="pagestamp_news_type">Research Highlight</span></p>
<p>A tablet-based screening tool that analyzes children’s behavior in response to specific video clips shows promise for enhancing early autism screening, according to a study supported in part by the National Institute of Mental Health. While early autism screening typically depends on parent questionnaires, data suggest the accuracy of these assessments may vary across settings and populations. Objective measurement tools, including digital technologies, could help improve screening in real-world settings and reduce disparities in early screening and identification.</p>
<h2>What did the researchers do?</h2>
<figure role="group" class="align-right">
<article class="media media--type-image media--view-mode-default">
<p>                        <span class="field field--name-field-media-image field--type-image field--label-hidden field__item">  <img decoding="async" loading="lazy" src="https://www.nimh.nih.gov/sites/default/files/images/toddler-watching-movies-on-the-app-2.png" width="4936" height="3697" alt="Toddler watching movies on the SenseToKnow app"/></p>
<p></span></p>
</article><figcaption>A toddler watching video clips via the SenseToKnow app. Photo courtsey of Geri Dawson.</figcaption></figure>
<p>In the study, researchers <a href="https://psychiatry.duke.edu/profile/geraldine-dawson" rel="external noreferrer noopener" target="_blank">Geraldine Dawson, Ph.D.</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://ece.duke.edu/faculty/guillermo-sapiro" rel="external noreferrer noopener" target="_blank">Guillermo Sapiro, Ph.D.</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, and colleagues at the <a href="https://autismcenter.duke.edu/" rel="external noreferrer noopener" target="_blank">Duke Center for Autism and Brain Development</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a> tested a tablet-based app called SenseToKnow. The app uses the tablet’s camera to capture a variety of child behaviors, including gaze patterns, facial expressions, head movements, blink rate, and whether the child responded to their name. According to the researchers, this multimodal approach allows them to capture the range of behavioral variations that children with autism may show.</p>
<p>During routine health care visits, toddlers watched specially designed video clips while the device recorded their behaviors and quantified them using computer vision, a type of artificial intelligence. The app then used machine learning to analyze the behavioral data, providing a diagnostic classification and a prediction confidence score indicating the reliability of that classification. The app also produced a quality score that indicated whether the app was administered correctly.</p>
<p>Study participants included 475 toddlers, ages 17 to 36 months. Of these toddlers, 49 later received an autism diagnosis and 98 later received a diagnosis of developmental delay and/or language delay without autism.</p>
<h2>What did the researchers find?</h2>
<p>Overall, the app showed high accuracy for classifying children with autism compared to neurotypical children, and even higher accuracy when the analyses included only the results that had high prediction confidence scores. Classification accuracy remained high when the analyses included data from children with developmental delay and/or language delay.</p>
<p>The app correctly classified nine children with autism who were not correctly identified using a standard early autism screening tool, the Modified Checklist for Autism in Toddlers (M-CHAT-Revised with Follow-Up). Classification accuracy increased further when the researchers combined the app analyses with input from the M-CHAT screening tool.</p>
<p>Importantly, classification accuracy was consistent regardless of the child’s sex, race, ethnicity, and age. According to the researchers, these initial findings suggest that objective digital screening tools may help reduce existing disparities in early autism screening, although more work is needed to establish the app’s performance across diverse groups.</p>
<h2>What do the results mean?</h2>
<p>Advantages of the SenseToKnow app include its usability in real-world settings and the fact that it provides actionable information. For example, a low quality score indicates the app wasn’t administered correctly and may need to be re-administered. On the other hand, a high prediction confidence score lends weight to the classification results and can help identify toddlers who are likely to benefit from further screening and evaluation.</p>
<p>Dawson and colleagues are now evaluating SenseToKnow in a variety of contexts. In another NIMH-funded study, the researchers are examining accuracy when parents administer the app at home on their own devices. They are also exploring whether the app can be used to detect early behavioral signs of autism in infants as young as 6-9 months.</p>
<p>The researchers emphasize that they do not intend for SenseToKnow to be the only data source for diagnosis. Rather, they envision autism screening as a multi-part process that includes parent-report questionnaires, objective digital screening tools, and other data sources such as electronic health records. They also note that screening is one part of a broader clinical pathway that includes provider training, careful implementation, and built-in links to services, supports, and interventions.</p>
<p>“We conclude that quantitative, objective, and scalable digital phenotyping offers promise in increasing the accuracy of autism screening and reducing disparities in access to diagnosis and intervention, complementing existing autism screening questionnaires,” Dawson and colleagues write.</p>
<h2>Reference</h2>
<p>Perochon, S., Di Martino, J.M., Carpenter, K.L.H. <em>et al.</em> (2023). Early detection of autism using digital behavioral phenotyping. <em>Nature Medicine, 29</em>, 2489–2497. <a href="https://doi.org/10.1038/s41591-023-02574-3" rel="external noreferrer noopener" target="_blank">https://doi.org/10.1038/s41591-023-02574-3</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a></p>
<h2>Funding</h2>
<p><a href="https://reporter.nih.gov/search/3s8-ewJlE0KuxAXUHYXuag/project-details/10670242" rel="external noopener" target="_blank">MH121329 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/76GQns3UW0mXzbgBvMcDhw/project-details/10440249" rel="external noopener" target="_blank">MH120093 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://reporter.nih.gov/search/WVH8EwnnsE-722YuNjQpZA/project-details/10698193" rel="external noopener" target="_blank">HD093074 <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a></p>
</p></div>
<p><br />
<br /><a href="https://www.nimh.nih.gov/news/science-news/2024/digital-autism-screening-tool-could-enhance-early-identification?utm_source=rss_readers&#038;utm_medium=rss&#038;utm_campaign=rss_summary" target="_blank" rel="noopener">Source link </a></p>
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		<title>Accelerating Science to Improve Early Autism Screening</title>
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		<dc:creator><![CDATA[Tony Ramos]]></dc:creator>
		<pubDate>Sat, 11 May 2024 21:38:58 +0000</pubDate>
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					<description><![CDATA[<p>April 23, 2024 • Feature Story • 75th Anniversary At a Glance Autism is a neurodevelopmental disorder that affects how people interact, communicate, and learn. Making early autism screening part of routine health care helps connect families to support and services as early as possible. Despite American Academy of Pediatrics guidelines, only a small fraction [&#8230;]</p>
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  <time class="pagestamp_news_time" datetime="2024-04-23">April 23, 2024</time><br />
  • <span class="pagestamp_news_type">Feature Story</span> • <span class="anniversary-tag">75th Anniversary</span></p>
<div class="group feature-box">
<p><strong>At a Glance</strong></p>
<ul>
<li>Autism is a neurodevelopmental disorder that affects how people interact, communicate, and learn.</li>
<li>Making early autism screening part of routine health care helps connect families to support and services as early as possible.</li>
<li>Despite American Academy of Pediatrics guidelines, only a small fraction of pediatricians reported screening for autism at well-child visits.</li>
<li>NIMH-supported efforts to close the gap between science and practice have yielded key insights into effective strategies for expanding early autism screening.</li>
<li>Researchers are identifying new tools for detection, new models for delivering services, and new strategies for embedding early autism screening and rapid referral into routine health care.</li>
</ul>
</div>
<p>As many parents of young children know all too well, visits to the pediatrician typically involve answering a series of questions. Health care providers may ask about the child’s eating and sleeping habits or about their progress toward walking, talking, and many other developmental milestones. Increasingly, they’re also asking questions that could help identify early signs of autism.</p>
<p><a href="https://www.nimh.nih.gov/health/topics/autism-spectrum-disorders-asd" data-entity-type="node" data-entity-uuid="e485146a-b8ce-4452-9c86-c214b4418e68" data-entity-substitution="canonical" title="Topic Page:  Autism Spectrum Disorders (ASD)" target="_blank" rel="noopener">Autism</a> is a neurodevelopmental disorder that affects how people interact, communicate, behave, and learn. It is known as a “spectrum” disorder because there is wide variation in the type and severity of symptoms people experience.</p>
<p>Today, thanks to research focused on embedding routine screening in well-baby checkups, the early signs of autism can be identified in children as young as 12–14 months. These efforts, many supported by the National Institute of Mental Health (NIMH), show that making early autism screening part of routine health care can have a significant impact on children and families, helping connect them to support and services as early as possible.</p>
<p>“This progress wasn’t inevitable or linear,” explains Lisa Gilotty, Ph.D., Chief of the <a href="https://www.nimh.nih.gov/about/organization/dtr/biomarker-and-intervention-development-for-childhood-onset-mental-disorders-branch/research-program-on-autism-spectrum-disorders" data-entity-type="node" data-entity-uuid="8238b4be-3c27-405f-9ff0-1f9b8a35f5e0" data-entity-substitution="canonical" title="Research Program on Autism Spectrum Disorders" target="_blank" rel="noopener">Research Program on Autism Spectrum Disorders</a> in the Division of Translational Research at NIMH. “Rather, it’s part of an evolving story that reflects the persistent, collective efforts of researchers and clinicians working to translate science into practice.”</p>
<h2>Identifying the disconnect</h2>
<p>The modern concept of autism as a neurodevelopmental disorder first emerged in the 1940s and coalesced into a diagnostic label by the 1980s. Diagnostic criteria evolved over time and, by the early 2000s, clinicians had evidence-based tools they could use to identify children with autism as early as 36 months. At the same time, evidence suggested that parents may notice signs even earlier, in the child’s second year of life.</p>
<p>“Reducing this gap—between observable signs and later identification and diagnosis—became an urgent target for researchers in the field,” said Dr. Gilotty. “The research clearly showed that kids who were identified early also had earlier access to supports and services, leading to better health and well-being over the long term.”</p>
<p>Researcher <a href="https://drexel.edu/autisminstitute/about/our-team/all-staff/Diana-Robins/" rel="external noreferrer noopener" target="_blank">Diana Robins, Ph.D.</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, then a doctoral student, wondered whether an evidence-based early screening tool might help close the gap. With <a href="https://reporter.nih.gov/search/-Wiky0Oi8kOgYD9MlwrrnA/project-details/6054728" rel="external noopener" target="_blank">support from NIMH <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, Robins and colleagues <a href="https://doi.org/10.1023/A:1010738829569" rel="external noreferrer noopener" target="_blank">developed the Modified Autism Checklist for Toddlers (M-CHAT)</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, which they introduced in 2001. They aimed to provide pediatricians with a simple screening measure that could identify children showing signs of autism as early as 24 months.</p>
<p>The science behind early screening continued to build and gain momentum over the next few years. By the mid-2000s, researchers were exploring the possibility of using various developmental screening tools—such as the Communication and Symbolic Behavior Scales, First Year Inventory, and Ages &amp; Stages Questionnaires—to identify early signs of autism.</p>
<p><a href="https://www.nimh.nih.gov/health/topics/autism-spectrum-disorders-asd" data-entity-type="node" data-entity-uuid="e485146a-b8ce-4452-9c86-c214b4418e68" data-entity-substitution="canonical" title="Topic Page:  Autism Spectrum Disorders (ASD)" target="_blank" rel="noopener"></p>
<article class="align-right media media--type-image media--view-mode-default"><span class="field field--name-field-media-image field--type-image field--label-hidden field__item">  <img decoding="async" loading="lazy" src="https://www.nimh.nih.gov/sites/default/files/images/2022-autism-updates-ig-4.jpg" width="1080" height="1080" alt="A young adult working on a computer gear with the text “Adults on the autism spectrum can benefit from services and supports that improve health and well-being across the lifespan.” The link points to nimh.nih.gov/autism."/></span></p>
</article>
<p></a></p>
<p>The growing body of evidence did not go unnoticed. In 2006, the American Academy of Pediatrics (AAP) issued evidence-based guidelines recommending <a href="https://www.aap.org/en/patient-care/autism/" rel="external noreferrer noopener" target="_blank">autism-specific screening</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a> for all children at the 18-month visit. In a later update, they recommended adding another autism-specific screening at the 24-month visit, recognizing that some children may start showing signs a bit later in development.</p>
<p>To the research community, these new guidelines signified a huge step forward for science-based practice. But this sense of progress was soon dashed by reality.</p>
<p>When researchers actually surveyed health care providers, they found that very few knew about or followed the AAP guidelines. For example, in a <a href="https://doi.org/10.1097/00004703-200604002-00006" rel="external noreferrer noopener" target="_blank">2006 study</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, 82% of pediatricians reported screening for general developmental delays, but only 8% reported screening for autism. Most of the pediatricians said they weren’t familiar with autism-specific screening tools, and many also cited a lack of time as a significant barrier to screening.</p>
<p>The disconnect between science and practice prompted concern in the research community. A series of conversations in scientific meetings and workshops led to a crystallizing moment for the staff at NIMH.</p>
<p>“There was a period of several years in which researchers would go off and do unfunded work and then bring it back to these meetings and say, ‘This is what I&#8217;ve been working on,’” said Dr. Gilotty. “It was an impetus for those of us at NIMH to say, ‘We’re going to do something about this.’”</p>
<h2>Bridging the gap</h2>
<p>Gilotty worked with colleagues Beverly Pringle, Ph.D., and Denise Juliano-Bult, M.S.W., who were part of NIMH’s Division of Services and Intervention Research (DSIR) at the time, to synthesize several file drawers’ worth of different measures, meeting notes, and research papers and distill them into an NIMH funding announcement.</p>
<p>The announcement, issued in 2013, focused on funding for autism services research in three critical age groups: <a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-14-100.html" rel="external noopener" target="_blank">toddlers <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, <a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-14-101.html" rel="external noopener" target="_blank">transition-age youth <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, and <a href="https://grants.nih.gov/grants/guide/rfa-files/RFA-MH-14-102.html" rel="external noopener" target="_blank">adults <i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>. NIMH ultimately funded five 5-year research projects that specifically examined screening and services in toddlers. The projects focused on interventions that emphasized early screening and connected children to further evaluation and services within the first two years of life.</p>
<p>In 2014, Denise Pintello, Ph.D., M.S.W., assumed the role of Chief of the <a href="https://www.nimh.nih.gov/about/organization/dsir/services-research-and-epidemiology-branch/child-and-adolescent-services-research-program" data-entity-type="node" data-entity-uuid="031d1b67-c657-4a92-ba7b-90b08f04a187" data-entity-substitution="canonical" title="Child and Adolescent Services Research Program" target="_blank" rel="noopener">Child and Adolescent Research Program</a> in DSIR. She directed the research portfolio that included these projects, which sparked an idea:</p>
<p>“It was such an exciting opportunity to connect these researchers because the projects were all funded together as a cluster,” she said. “I thought, ‘Let’s encourage these exceptional researchers to work closely together.’”</p>
<p>At NIMH’s invitation, the researchers on the projects united to form the ASD Pediatric, Early Detection, Engagement, and Services (ASD PEDS) Research Network. Although the ASD PEDS researchers were using different research approaches in a range of settings, coming together as a network allowed them to share knowledge and resources, analyze data across research sites, and <a href="https://doi.org/10.1177/1362361318766238" rel="external noreferrer noopener" target="_blank">publish their findings together</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>. The researchers also worked together to identify ways that their data could help address noticeable gaps in the evidence base.</p>
<h2>Building on the evidence</h2>
<p>Together, the ASD PEDS studies have screened more than 109,000 children, yielding critical insights into the most effective strategies for expanding early autism screening.</p>
<p>For example, <a href="https://doi.org/10.1016/j.jpeds.2021.04.041" rel="external noreferrer noopener" target="_blank">an ASD PEDS study</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a> led by <a href="https://profiles.ucsd.edu/karen.pierce" rel="external noreferrer noopener" target="_blank">Karen Pierce, Ph.D.</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, showed the effectiveness of integrating screening, evaluation, and treatment (SET) in an approach called the Get SET Early model.</p>
<figure role="group" class="align-center"><a href="https://neurosciences.ucsd.edu/centers-programs/autism/early/screening.html" rel="external noreferrer noopener" target="_blank"></p>
<article class="media media--type-image media--view-mode-default"><span class="field field--name-field-media-image field--type-image field--label-hidden field__item">  <img decoding="async" loading="lazy" src="https://www.nimh.nih.gov/sites/default/files/images/early-get-set-model.jpg" width="900" height="515" alt="Illustration of the steps in the Get SET Early model"/></span></p>
</article>
<p></a><figcaption>Key components in the Get SET Early model. Image courtesy of Karen Pierce.</figcaption></figure>
<p> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a></p>
<p>Working with 203 pediatricians in San Diego County, California, Pierce and colleagues devised a standardized process that the providers could use to screen toddlers for autism at their 12-, 18-, and 24-month well-child visits. The researchers also developed a digital screening platform that scored the results automatically and gave clear guidelines for deciding when to refer a child for further evaluation.</p>
<p>These improvements boosted the rate at which providers referred children for additional evaluation and sped up the transition from screening to evaluation and services. The study also showed that autism can be identified in children as young as 12–14 months old, several years earlier than the nationwide average of 4 years.</p>
<p>This and other studies showed that incorporating universal early screening for autism into regular health care visits was not only feasible but effective. Working closely with health care providers allowed researchers to build trust with the providers and address their concerns.</p>
<p>“There is this sense that if you sit down and really talk with pediatricians, you can bring them into the fold,” said Dr. Gilotty. “Once you get some key people, you get a few more and a few more, and then it becomes something that ‘everybody’ is doing.”</p>
<h2>Meeting the need</h2>
<p>At the same time, the ASD PEDS studies have also explored ways to reach families with young children outside of primary care settings. Numerous studies have shown that some families are much less likely to have access to early screening and evaluation, including non-English-speaking families, families with low household incomes, and families from certain racial and ethnic minority groups.</p>
<p>“Screening is most effective when everyone who needs it has access to it,” said Dr. Pintello. “Addressing these disparities is a critical issue in the field and NIMH’s efforts have prioritized focusing on underserved families.”</p>
<p>One way to accomplish this is to integrate standardized universal screening into systems that are already serving these families. For example, in <a href="https://www.nimh.nih.gov/news/science-news/2022/multistage-autism-screening-in-early-intervention-settings-may-reduce-disparities" data-entity-type="node" data-entity-uuid="6a18e25a-7e0c-4d3e-8b60-686abe34abbd" data-entity-substitution="canonical" title="Multistage Autism Screening in Early Intervention Settings May Reduce Disparities" target="_blank" rel="noopener">one study</a>, ASD PEDS investigators <a href="https://www.umb.edu/directory/alicescarter/" rel="external noreferrer noopener" target="_blank">Alice Carter, Ph.D.</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, and <a href="https://www.bu.edu/sph/profile/radley-sheldrick/" rel="external noreferrer noopener" target="_blank">Radley Christopher Sheldrick, Ph.D.</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a>, worked with the Massachusetts Department of Public Health to implement an evidence-based screening procedure at three federally funded early intervention sites.</p>
<p>The researchers developed a multi-part screening and diagnosis process that included both clinicians and caregivers as key decision-makers. They hypothesized that this standardized process would minimize procedural variations across the early intervention sites and help to reduce existing disparities in ASD screening and diagnosis.</p>
<p>The results suggested their hunch was correct. All three study sites showed an increase in the rate of autism diagnosis with the new procedure in place, compared with other intervention sites that served similar communities. Importantly, the standardized procedure seemed to address existing disparities in screening and diagnosis. The increased rate of diagnosis observed among Spanish-speaking families was more than double the increase observed among non-Spanish-speaking families.</p>
<h2>Looking to the future</h2>
<p>Researchers are continuing to explore the best ways to put existing evidence-based screening methods into practice. At the same time, NIMH is also focused on research that seeks to develop new and improved screening tools. Evidence from neuroimaging and eye tracking studies suggests that, although the age at which observable features of autism emerge does vary, subtle signs can be detected in the first year of life. NIMH is <a href="https://www.nimh.nih.gov/news/science-news/2019/nih-awards-funding-for-early-autism-screening" data-entity-type="node" data-entity-uuid="4b498d0b-fde5-469e-a988-b32606be3526" data-entity-substitution="canonical" title="NIH Awards Funding for Early Autism Screening" target="_blank" rel="noopener">supporting a suite of projects</a> that aim to validate screening tools that can be used to identify signs of autism before a child’s first birthday.</p>
<p>“In other words, are there measures we can use to identify signs even before parents and clinicians begin to notice them?” explained Dr. Gilotty. “This is the critical question because the earlier kids are identified, the earlier they can be connected with support.”</p>
<p>These projects leverage sophisticated digital tools to detect subtle patterns in infant behavior. For example, researchers are using technology to identify patterns in what infants look at, the vocalizations they make, and how they move. They’re using technology to examine synchrony in infant–caregiver interactions. And they’re developing digital screening tools that can be administered via telehealth platforms.</p>
<p>The hope is that new tools identified and validated in this first stage will go on to be tested in large-scale, real-world contexts, reflecting a continuous pipeline of research that goes from science to practice.</p>
<p>“As a result of targeted research funded by NIMH over the last 10 years, we are seeing new tools for detection, new models for delivering services, and new strategies for embedding early screening and rapid referral into routine health care,” said Dr. Pintello.</p>
<p>“I feel like it’s just the beginning of the story—we are just now seeing the impact of bringing science-based tools and practices into the hands of health care providers. Over the next few years, we hope that ongoing efforts to bridge science and practice will help us meet the unique needs of children at the exact time that they need services.”</p>
<h2>Publications</h2>
<p>Broder Fingert, S., Carter, A., Pierce, K., Stone, W. L., Wetherby, A., Scheldrick, C., Smith, C., Bacon, E., James, S. N., Ibañez, L., &amp; Feinberg, E. (2019). Implementing systems-based innovations to improve access to early screening, diagnosis, and treatment services for children with autism spectrum disorder: An Autism Spectrum Disorder Pediatric, Early Detection, Engagement, and Services network study. <em>Autism</em>,<em>23</em>(3), 653–664. <a href="https://doi.org/10.1177/1362361318766238" rel="external noreferrer noopener" target="_blank">https://doi.org/10.1177/1362361318766238</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a></p>
<p>DosReis, S., Weiner, C., Johnson, L., &amp; Newschaffer, C. (2006). Autism spectrum disorder screening and management practices among general pediatric providers. <em>Journal of Developmental and Behavioral Pediatrics</em>,<em> 27</em>(2), S88–S94. <a href="https://doi.org/10.1097/00004703-200604002-00006" rel="external noreferrer noopener" target="_blank">https://doi.org/10.1097/00004703-200604002-00006</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a></p>
<p>Eisenhower, A., Martinez Pedraza, F., Sheldrick, R. C., Frenette, E., Hoch, N., Brunt, S., &amp; Carter, A. S. (2021). Multi-stage screening in early intervention: A critical strategy for improving ASD identification and addressing disparities. <em>Journal of Autism and Developmental Disorders, 51</em>, 868–883. <a href="https://doi.org/10.1007/s10803-020-04429-z" rel="external noreferrer noopener" target="_blank">https://doi.org/10.1007/s10803-020-04429-z</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a></p>
<p>Feinberg, E., Augustyn, M., Broder-Fingert, S., Bennett, A., Weitzman, C., Kuhn, J., Hickey, E., Chu, A., Levinson, J., Sandler Eilenberg, J., Silverstein, M., Cabral, H. J., Patts, G., Diaz-Linhart, Y., Fernandez-Pastrana, I., Rosenberg, J., Miller, J. S., Guevara, J. P., Fenick, A. M., &amp; Blum, N. J. (2021). Effect of family navigation on diagnostic ascertainment among children at risk for autism: A randomized clinical trial from DBPNet. <em>JAMA Pediatrics</em>,<em> 175</em>(3), 243–250. <a href="https://doi.org/10.1001/jamapediatrics.2020.5218" rel="external noreferrer noopener" target="_blank">https://doi.org/10.1001/jamapediatrics.2020.5218</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a></p>
<p>Pierce, K., Gazestani, V., Bacon, E., Courchesne, E., Cheng, A., Barnes, C. C., Nalabolu, S., Cha, D., Arias, S., Lopez, L., Pham, C., Gaines, K., Gyurjyan, G., Cook-Clark, T., &amp; Karins, K. (2021). Get SET Early to identify and treatment refer autism spectrum disorder at 1 year and discover factors that influence early diagnosis. <em>The Journal of Pediatrics, 236</em>, 179–188. <a href="https://doi.org/10.1016/j.jpeds.2021.04.041" rel="external noreferrer noopener" target="_blank">https://doi.org/10.1016/j.jpeds.2021.04.041</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a></p>
<p>Robins, D. L., Fein, D., Barton, M. L., &amp; Green, J. A. (2001). The Modified Checklist for Autism in Toddlers: An initial study investigating the early detection of autism and pervasive developmental disorders. <em>Journal of Autism and Developmental Disorders</em>,<em> 31</em>, 131–144. <a href="https://doi.org/10.1023/A:1010738829569" rel="external noreferrer noopener" target="_blank">https://doi.org/10.1023/A:1010738829569</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a></p>
<p>Sheldrick, R. C., Carter, A. S., Eisenhower, A., Mackie, T. I., Cole, M. B., Hoch, N., Brunt, S., &amp; Pedraza, F. M. (2022). Effectiveness of screening in early intervention settings to improve diagnosis of autism and reduce health disparities. <em>JAMA Pediatrics</em>,<em> 176</em>(3)<em>, </em>262–269. <a href="https://doi.org/10.1001/jamapediatrics.2021.5380" rel="external noreferrer noopener" target="_blank">https://doi.org/10.1001/jamapediatrics.2021.5380</a> <a href="http://www.nimh.nih.gov/site-info/policies#part_2717" title="Exit Disclaimer" class="exit-disclaimer" target="_blank" rel="noopener"><i class="fa-solid fa-arrow-up-right-from-square ext-link-icon"/></a></p>
<h2>Learn more</h2>
</p></div>
<p><br />
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		<title>Immersed in Print in Early Modern F&#8230;</title>
		<link>https://bookandauthornews.com/immersed-in-print-in-early-modern-f/</link>
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		<dc:creator><![CDATA[Tony Ramos]]></dc:creator>
		<pubDate>Sat, 30 Mar 2024 08:18:16 +0000</pubDate>
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					<description><![CDATA[<p>Anxieties about the fate of reading in the digital age reveal how deeply our views of the moral and intellectual benefits of reading are tied to print. These views take root in a conception of reading as an immersive activity, exemplified by the experience of &#8220;losing oneself in a book.&#8221; Against the backdrop of digital [&#8230;]</p>
<p>The post <a rel="nofollow" href="https://bookandauthornews.com/immersed-in-print-in-early-modern-f/">Immersed in Print in Early Modern F&#8230;</a> appeared first on <a rel="nofollow" href="https://bookandauthornews.com">Book and Author News</a>.</p>
]]></description>
										<content:encoded><![CDATA[<p> <br />
<br /><img decoding="async" src="http://www.sup.org/img/covers/large/pid_37154.jpg" /></p>
<div id="description">
<div class="readable">
<p>Anxieties about the fate of reading in the digital age reveal how deeply our views of the moral and intellectual benefits of reading are tied to print. These views take root in a conception of reading as an immersive activity, exemplified by the experience of &#8220;losing oneself in a book.&#8221; Against the backdrop of digital distraction and fragmentation, such immersion leads readers to become more focused, collected, and empathetic.</p>
<p>How did we come to see the printed book as especially suited to deliver this experience? Print-based reading practices have historically included a wide range of modes, not least the disjointed scanning we associate today with electronic text. In the context of religious practice, literacy&#8217;s benefits were presumed to lie in such random-access retrieval, facilitated by indexical tools like the numbering of Biblical chapters and verses. It was this didactic, hunt-and-peck reading that bound readers to communities.</p>
<p>Exploring key evolutions in print in 17th- and 18th-century France, from typeface, print runs, and format to punctuation and the editorial adaptation of manuscript and oral forms in print, this book argues that typographic developments upholding the transparency of the printed medium were decisive for the ascendancy of immersive reading as a dominant paradigm that shaped modern perspectives on reading and literacy.</p>
</div>
<p class="readable-heading">About the author</p>
<div class="readable">
<p><b>Geoffrey Turnovsky</b>  is Associate Professor of French at the University of Washington, Seattle. He is the author of <i>The Literary Market: Authorship and Modernity in the Old Regime</i> (2011).</p>
</div></div>
<div id="reviews">
<p>&#8220;This book will shift discussions of the public sphere, imagined communities, and the role of the public intellectual. In the looming controversies surrounding AI in education, this book makes the case against fetishizing one historically specific kind of reading.&#8221;</p>
<p class="review-attribution">—George Hoffmann, University of Michigan</p>
<p>&#8220;This is a fascinating study. <i>Reading Typographically</i> is an important contribution to our histories of reading, and essential for students and historians of reading.&#8221;</p>
<p class="review-attribution">—Jennifer Richards, University of Cambridge</p>
<p>&#8220;This provocative and exciting book considers how typographical devices were used for erasing the perception of the materiality of the text and create an unmediated relationship between the reader and characters&#8217; voices or the writer&#8217;s heart. Important and innovative.&#8221;</p>
<p class="review-attribution">—Roger Chartier, Collège de France</p>
</div>
<p><br />
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<p>The post <a rel="nofollow" href="https://bookandauthornews.com/immersed-in-print-in-early-modern-f/">Immersed in Print in Early Modern F&#8230;</a> appeared first on <a rel="nofollow" href="https://bookandauthornews.com">Book and Author News</a>.</p>
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		<title>‘It’s about being able to say goodbye’: Spanish graphic novel explores early Franco-era reprisals &#124; Spain</title>
		<link>https://bookandauthornews.com/its-about-being-able-to-say-goodbye-spanish-graphic-novel-explores-early-franco-era-reprisals-spain/</link>
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		<dc:creator><![CDATA[Tony Ramos]]></dc:creator>
		<pubDate>Mon, 08 Jan 2024 23:51:43 +0000</pubDate>
				<category><![CDATA[Book and Literature News]]></category>
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					<description><![CDATA[<p>At the beginning of the new Spanish graphic novel El abismo del olvido (The Abyss of Forgetting), a murdered man climbs out of his grave, lights a cigarette and takes stock of the past eight decades. “When western archaeologists opened the tombs of ancient Egypt, it was said that the souls of their occupants had [&#8230;]</p>
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<p class="dcr-1kas69x"><span style="color:var(--drop-cap);font-weight:700;" class="dcr-11l45yn">A</span>t the beginning of the new Spanish graphic novel <em class="dcr-1kas69x">El abismo del olvido</em> (The Abyss of Forgetting), a murdered man climbs out of his grave, lights a cigarette and takes stock of the past eight decades. “When western archaeologists opened the tombs of ancient Egypt, it was said that the souls of their occupants had been freed after millennia of silence,” he says. “In a way, the same thing is happening to us. All we did was wait in silence for more than 70 years.”</p>
<p class="dcr-1kas69x">José Celda – Pepe to his friends – was <a href="https://www.theguardian.com/world/2022/may/15/hes-coming-home-mass-grave-in-valencia-gives-up-francos-victims" data-link-name="in body link" target="_blank" rel="noopener">shot dead against a wall</a> in the small Valencian town of Paterna at five in the afternoon on 14 September 1940. The 45-year-old farmer, whose body was buried in a mass grave, was one of the <a href="https://www.theguardian.com/world/2023/oct/16/the-memory-letters-spain-franco-victims" data-link-name="in body link" target="_blank" rel="noopener">thousands of </a><em class="dcr-1kas69x"><a href="https://www.theguardian.com/world/2023/oct/16/the-memory-letters-spain-franco-victims" data-link-name="in body link" target="_blank" rel="noopener">represaliados</a></em>, or victims of reprisals, who were murdered by the Franco regime well after the end of the civil war in April 1939.</p>
<p class="dcr-1kas69x"><em class="dcr-1kas69x">El abismo del olvido</em>, a collaboration between the <a href="https://www.theguardian.com/culture/2021/may/28/kapow-batman-takes-holiday-in-benidorm-in-dc-comics-anthology" data-link-name="in body link" target="_blank" rel="noopener">graphic artist Paco Roca</a> and the journalist Rodrigo Terrasa<em class="dcr-1kas69x">, </em>examines the atrocities and the generational agonies they inflicted, and continue to inflict, on the families of the dead.</p>
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<div id="img-2" class="dcr-1t8m8f2"><picture class="dcr-evn1e9"><source srcset="https://i.guim.co.uk/img/media/8055989bf12b7a3ba573cc8327ad4129e943ff53/0_0_1890_1339/master/1890.jpg?width=880&amp;dpr=2&amp;s=none" media="(min-width: 1300px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 1300px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/8055989bf12b7a3ba573cc8327ad4129e943ff53/0_0_1890_1339/master/1890.jpg?width=880&amp;dpr=1&amp;s=none" media="(min-width: 1300px)"/><source srcset="https://i.guim.co.uk/img/media/8055989bf12b7a3ba573cc8327ad4129e943ff53/0_0_1890_1339/master/1890.jpg?width=800&amp;dpr=2&amp;s=none" media="(min-width: 1140px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 1140px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/8055989bf12b7a3ba573cc8327ad4129e943ff53/0_0_1890_1339/master/1890.jpg?width=800&amp;dpr=1&amp;s=none" media="(min-width: 1140px)"/><source srcset="https://i.guim.co.uk/img/media/8055989bf12b7a3ba573cc8327ad4129e943ff53/0_0_1890_1339/master/1890.jpg?width=640&amp;dpr=2&amp;s=none" media="(min-width: 980px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 980px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/8055989bf12b7a3ba573cc8327ad4129e943ff53/0_0_1890_1339/master/1890.jpg?width=640&amp;dpr=1&amp;s=none" media="(min-width: 980px)"/><source srcset="https://i.guim.co.uk/img/media/8055989bf12b7a3ba573cc8327ad4129e943ff53/0_0_1890_1339/master/1890.jpg?width=620&amp;dpr=2&amp;s=none" media="(min-width: 660px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 660px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/8055989bf12b7a3ba573cc8327ad4129e943ff53/0_0_1890_1339/master/1890.jpg?width=620&amp;dpr=1&amp;s=none" media="(min-width: 660px)"/><source srcset="https://i.guim.co.uk/img/media/8055989bf12b7a3ba573cc8327ad4129e943ff53/0_0_1890_1339/master/1890.jpg?width=605&amp;dpr=2&amp;s=none" media="(min-width: 480px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 480px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/8055989bf12b7a3ba573cc8327ad4129e943ff53/0_0_1890_1339/master/1890.jpg?width=605&amp;dpr=1&amp;s=none" media="(min-width: 480px)"/><source srcset="https://i.guim.co.uk/img/media/8055989bf12b7a3ba573cc8327ad4129e943ff53/0_0_1890_1339/master/1890.jpg?width=445&amp;dpr=2&amp;s=none" media="(min-width: 320px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 320px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/8055989bf12b7a3ba573cc8327ad4129e943ff53/0_0_1890_1339/master/1890.jpg?width=445&amp;dpr=1&amp;s=none" media="(min-width: 320px)"/><img decoding="async" alt="Scenes from El abismo del olvido" src="https://i.guim.co.uk/img/media/8055989bf12b7a3ba573cc8327ad4129e943ff53/0_0_1890_1339/master/1890.jpg?width=445&amp;dpr=1&amp;s=none" width="445" height="315.26719576719574" loading="lazy" class="dcr-evn1e9"/></picture></div><figcaption class="dcr-1csa5qs"><span class="dcr-15haadn"><svg width="18" height="13" viewbox="0 0 18 13"><path d="M18 3.5v8l-1.5 1.5h-15l-1.5-1.5v-8l1.5-1.5h3.5l2-2h4l2 2h3.5l1.5 1.5zm-9 7.5c1.9 0 3.5-1.6 3.5-3.5s-1.6-3.5-3.5-3.5-3.5 1.6-3.5 3.5 1.6 3.5 3.5 3.5z"/></svg></span><span class="dcr-1qvd3m6">Thousands of <em>represaliados</em> were murdered by the Franco regime after the end of the Spanish civil war.</span> Illustration: Astiberri</figcaption></figure>
<p class="dcr-1kas69x">As well as telling Celda’s story, the comic chronicles the tireless and solitary struggle that his daughter Pepica waged to fulfil her mother’s wishes for his bones to be found and reinterred with hers.</p>
<p class="dcr-1kas69x">Pepica Celda, who was eight when her father was murdered, began her quest after the socialist government of José Luis Rodríguez Zapatero introduced its <a href="https://www.theguardian.com/world/2007/nov/01/spain.international2" data-link-name="in body link" target="_blank" rel="noopener">landmark 2007 historical memory law</a> that was intended to bring a measure of justice and comfort to Franco’s victims. She made headlines a few years later for becoming the last person in Spain to secure a government subsidy for her search before the conservative People’s party (PP) took power in 2011 and <a href="https://www.theguardian.com/world/2021/oct/09/spain-bodies-franco-victims-dictator-mass-graves" data-link-name="in body link" target="_blank" rel="noopener">ended the funding</a>.</p>
<p class="dcr-1kas69x">Terrasa, who interviewed Pepica Celda in 2013 after her father’s remains had finally been identified in Paterna cemetery’s mass grave No 126, was enthralled by her story and her resilience in the face of so much time, opposition and bureaucracy. As the years went by, Terrasa became more and more convinced there was a book to be written on Pepica and her father. That book, he soon decided, should be a graphic novel, preferably drawn by his friend Roca.</p>
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<div id="img-3" class="dcr-1t8m8f2"><picture class="dcr-evn1e9"><source srcset="https://i.guim.co.uk/img/media/5fa85e0b9789ad165183c29bf9f0b6ec4834cfa3/0_400_6000_3600/master/6000.jpg?width=620&amp;dpr=2&amp;s=none" media="(min-width: 660px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 660px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/5fa85e0b9789ad165183c29bf9f0b6ec4834cfa3/0_400_6000_3600/master/6000.jpg?width=620&amp;dpr=1&amp;s=none" media="(min-width: 660px)"/><source srcset="https://i.guim.co.uk/img/media/5fa85e0b9789ad165183c29bf9f0b6ec4834cfa3/0_400_6000_3600/master/6000.jpg?width=605&amp;dpr=2&amp;s=none" media="(min-width: 480px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 480px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/5fa85e0b9789ad165183c29bf9f0b6ec4834cfa3/0_400_6000_3600/master/6000.jpg?width=605&amp;dpr=1&amp;s=none" media="(min-width: 480px)"/><source srcset="https://i.guim.co.uk/img/media/5fa85e0b9789ad165183c29bf9f0b6ec4834cfa3/0_400_6000_3600/master/6000.jpg?width=445&amp;dpr=2&amp;s=none" media="(min-width: 320px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 320px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/5fa85e0b9789ad165183c29bf9f0b6ec4834cfa3/0_400_6000_3600/master/6000.jpg?width=445&amp;dpr=1&amp;s=none" media="(min-width: 320px)"/><img decoding="async" alt="Rodrigo Terrasa and Paco Roca" src="https://i.guim.co.uk/img/media/5fa85e0b9789ad165183c29bf9f0b6ec4834cfa3/0_400_6000_3600/master/6000.jpg?width=445&amp;dpr=1&amp;s=none" width="445" height="267" loading="lazy" class="dcr-evn1e9"/></picture></div><figcaption class="dcr-14i6lp8"><span class="dcr-15haadn"><svg width="18" height="13" viewbox="0 0 18 13"><path d="M18 3.5v8l-1.5 1.5h-15l-1.5-1.5v-8l1.5-1.5h3.5l2-2h4l2 2h3.5l1.5 1.5zm-9 7.5c1.9 0 3.5-1.6 3.5-3.5s-1.6-3.5-3.5-3.5-3.5 1.6-3.5 3.5 1.6 3.5 3.5 3.5z"/></svg></span><span class="dcr-1qvd3m6">Rodrigo Terrasa and Paco Roca: ‘This is about so many families that only have that very human urge to … bury their loved ones with dignity.’</span> Photograph: Alberto Di Lolli</figcaption></figure>
<p class="dcr-1kas69x">The problem was that the artist had a string of work commitments and was not fully convinced by his friend’s proposal. All that changed when the pair sat down with Pepica Celda.</p>
<p class="dcr-1kas69x">“Listening to what she said first-hand won me over,” Roca said. “You had this woman talking about her motivation and her story; about how her father had been murdered during the dictatorship.”</p>
<p class="dcr-1kas69x">But it was not only her story that struck him. “We got really emotional when she told us about the last time she’d seen her father,” he said. “Before she went to see him in prison, her aunt asked her to promise not to cry so that her father’s last image wouldn’t be of her in tears. She said she swallowed those tears and had never cried since.”</p>
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<div id="img-4" class="dcr-1t8m8f2"><picture class="dcr-evn1e9"><source srcset="https://i.guim.co.uk/img/media/bddd0f74dfdb31451a1f91ef664bc0b115e47740/0_0_1890_1339/master/1890.jpg?width=880&amp;dpr=2&amp;s=none" media="(min-width: 1300px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 1300px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/bddd0f74dfdb31451a1f91ef664bc0b115e47740/0_0_1890_1339/master/1890.jpg?width=880&amp;dpr=1&amp;s=none" media="(min-width: 1300px)"/><source srcset="https://i.guim.co.uk/img/media/bddd0f74dfdb31451a1f91ef664bc0b115e47740/0_0_1890_1339/master/1890.jpg?width=800&amp;dpr=2&amp;s=none" media="(min-width: 1140px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 1140px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/bddd0f74dfdb31451a1f91ef664bc0b115e47740/0_0_1890_1339/master/1890.jpg?width=800&amp;dpr=1&amp;s=none" media="(min-width: 1140px)"/><source srcset="https://i.guim.co.uk/img/media/bddd0f74dfdb31451a1f91ef664bc0b115e47740/0_0_1890_1339/master/1890.jpg?width=640&amp;dpr=2&amp;s=none" media="(min-width: 980px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 980px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/bddd0f74dfdb31451a1f91ef664bc0b115e47740/0_0_1890_1339/master/1890.jpg?width=640&amp;dpr=1&amp;s=none" media="(min-width: 980px)"/><source srcset="https://i.guim.co.uk/img/media/bddd0f74dfdb31451a1f91ef664bc0b115e47740/0_0_1890_1339/master/1890.jpg?width=620&amp;dpr=2&amp;s=none" media="(min-width: 660px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 660px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/bddd0f74dfdb31451a1f91ef664bc0b115e47740/0_0_1890_1339/master/1890.jpg?width=620&amp;dpr=1&amp;s=none" media="(min-width: 660px)"/><source srcset="https://i.guim.co.uk/img/media/bddd0f74dfdb31451a1f91ef664bc0b115e47740/0_0_1890_1339/master/1890.jpg?width=605&amp;dpr=2&amp;s=none" media="(min-width: 480px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 480px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/bddd0f74dfdb31451a1f91ef664bc0b115e47740/0_0_1890_1339/master/1890.jpg?width=605&amp;dpr=1&amp;s=none" media="(min-width: 480px)"/><source srcset="https://i.guim.co.uk/img/media/bddd0f74dfdb31451a1f91ef664bc0b115e47740/0_0_1890_1339/master/1890.jpg?width=445&amp;dpr=2&amp;s=none" media="(min-width: 320px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 320px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/bddd0f74dfdb31451a1f91ef664bc0b115e47740/0_0_1890_1339/master/1890.jpg?width=445&amp;dpr=1&amp;s=none" media="(min-width: 320px)"/><img decoding="async" alt="Scenes from El abismo del olvido" src="https://i.guim.co.uk/img/media/bddd0f74dfdb31451a1f91ef664bc0b115e47740/0_0_1890_1339/master/1890.jpg?width=445&amp;dpr=1&amp;s=none" width="445" height="315.26719576719574" loading="lazy" class="dcr-evn1e9"/></picture></div><figcaption class="dcr-1csa5qs"><span class="dcr-15haadn"><svg width="18" height="13" viewbox="0 0 18 13"><path d="M18 3.5v8l-1.5 1.5h-15l-1.5-1.5v-8l1.5-1.5h3.5l2-2h4l2 2h3.5l1.5 1.5zm-9 7.5c1.9 0 3.5-1.6 3.5-3.5s-1.6-3.5-3.5-3.5-3.5 1.6-3.5 3.5 1.6 3.5 3.5 3.5z"/></svg></span><span class="dcr-1qvd3m6">Scenes from El abismo del olvido (The Abyss of Forgetting).</span> Illustration: Astiberri</figcaption></figure>
<p class="dcr-1kas69x">Roca soon realised that Pepica Celda’s story would have an appalling resonance for many other people. “This isn’t just about Pepica, it’s about so many other families that only have that very human urge to be able to get their loved ones out of a mass grave and bury them with dignity,” he said. “It’s about being able to say goodbye and to close up those wounds and turn the page. Take away all the politics – which muddy all this in <a href="https://www.theguardian.com/world/spain" data-link-name="in body link" data-component="auto-linked-tag" target="_blank" rel="noopener">Spain</a> – and it’s just something totally human that any of us would want to do.”</p>
<p class="dcr-1kas69x">No less important a character in the book is the extraordinary figure of Leoncio Badía, a young republican gravedigger who risked his life by logging the identities of the murdered men he buried in Paterna and snipping off locks of hair and fragments of their clothing to give to their grieving families.</p>
<p class="dcr-1kas69x">Badía’s bravery and kindness was never forgotten by the families he helped, but his actions only came fully to light a decade ago when archaeologists exhuming the graves he had dug came across tiny glass bottles that had been buried with the bodies. The bottles contained rolled-up pieces of paper with the name of the victim and the date of their death; Badía had hidden them on the bodies so that they could be identified in the future.</p>
<p class="dcr-1kas69x">Although the novel draws its emotive power from images of Badía’s little bottles, of Pepe Celda’s black hair turning white as he waits for death and of his daughter’s still-denied tears, its digressive reflections also invite the reader to consider the importance of a decent burial. Interspersed with their stories are pages that revisit the Iliad and Achilles’ furious and vengeful refusal to surrender the body of Hector to his grieving family.</p>
<figure id="761b962f-0c35-4100-9d76-19e07a41b08b" data-spacefinder-role="showcase" data-spacefinder-type="model.dotcomrendering.pageElements.ImageBlockElement" class=" dcr-5h0uf4">
<div id="img-5" class="dcr-1t8m8f2"><picture class="dcr-evn1e9"><source srcset="https://i.guim.co.uk/img/media/3f42ffc3c812f73bd554533c203502e4e4f0e7f6/0_0_1890_1339/master/1890.jpg?width=880&amp;dpr=2&amp;s=none" media="(min-width: 1300px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 1300px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/3f42ffc3c812f73bd554533c203502e4e4f0e7f6/0_0_1890_1339/master/1890.jpg?width=880&amp;dpr=1&amp;s=none" media="(min-width: 1300px)"/><source srcset="https://i.guim.co.uk/img/media/3f42ffc3c812f73bd554533c203502e4e4f0e7f6/0_0_1890_1339/master/1890.jpg?width=800&amp;dpr=2&amp;s=none" media="(min-width: 1140px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 1140px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/3f42ffc3c812f73bd554533c203502e4e4f0e7f6/0_0_1890_1339/master/1890.jpg?width=800&amp;dpr=1&amp;s=none" media="(min-width: 1140px)"/><source srcset="https://i.guim.co.uk/img/media/3f42ffc3c812f73bd554533c203502e4e4f0e7f6/0_0_1890_1339/master/1890.jpg?width=640&amp;dpr=2&amp;s=none" media="(min-width: 980px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 980px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/3f42ffc3c812f73bd554533c203502e4e4f0e7f6/0_0_1890_1339/master/1890.jpg?width=640&amp;dpr=1&amp;s=none" media="(min-width: 980px)"/><source srcset="https://i.guim.co.uk/img/media/3f42ffc3c812f73bd554533c203502e4e4f0e7f6/0_0_1890_1339/master/1890.jpg?width=620&amp;dpr=2&amp;s=none" media="(min-width: 660px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 660px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/3f42ffc3c812f73bd554533c203502e4e4f0e7f6/0_0_1890_1339/master/1890.jpg?width=620&amp;dpr=1&amp;s=none" media="(min-width: 660px)"/><source srcset="https://i.guim.co.uk/img/media/3f42ffc3c812f73bd554533c203502e4e4f0e7f6/0_0_1890_1339/master/1890.jpg?width=605&amp;dpr=2&amp;s=none" media="(min-width: 480px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 480px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/3f42ffc3c812f73bd554533c203502e4e4f0e7f6/0_0_1890_1339/master/1890.jpg?width=605&amp;dpr=1&amp;s=none" media="(min-width: 480px)"/><source srcset="https://i.guim.co.uk/img/media/3f42ffc3c812f73bd554533c203502e4e4f0e7f6/0_0_1890_1339/master/1890.jpg?width=445&amp;dpr=2&amp;s=none" media="(min-width: 320px) and (-webkit-min-device-pixel-ratio: 1.25), (min-width: 320px) and (min-resolution: 120dpi)"/><source srcset="https://i.guim.co.uk/img/media/3f42ffc3c812f73bd554533c203502e4e4f0e7f6/0_0_1890_1339/master/1890.jpg?width=445&amp;dpr=1&amp;s=none" media="(min-width: 320px)"/><img decoding="async" alt="Scenes from El abismo del olvido" src="https://i.guim.co.uk/img/media/3f42ffc3c812f73bd554533c203502e4e4f0e7f6/0_0_1890_1339/master/1890.jpg?width=445&amp;dpr=1&amp;s=none" width="445" height="315.26719576719574" loading="lazy" class="dcr-evn1e9"/></picture></div><figcaption class="dcr-1csa5qs"><span class="dcr-15haadn"><svg width="18" height="13" viewbox="0 0 18 13"><path d="M18 3.5v8l-1.5 1.5h-15l-1.5-1.5v-8l1.5-1.5h3.5l2-2h4l2 2h3.5l1.5 1.5zm-9 7.5c1.9 0 3.5-1.6 3.5-3.5s-1.6-3.5-3.5-3.5-3.5 1.6-3.5 3.5 1.6 3.5 3.5 3.5z"/></svg></span><span class="dcr-1qvd3m6">The novel invites the reader to consider the importance of a decent burial.</span> Illustration: Astiberri</figcaption></figure>
<p class="dcr-1kas69x">Terrasa, who knows only too well that today’s newspapers “are the wrappers for tomorrow’s sandwiches”, hopes the form, content and poignant simplicity of <em class="dcr-1kas69x">El abismo del olvido </em>will cut through some of the political noise. He and Roca also hope it will remind people of what happened, and of the thousands of Spaniards who still lie in mass graves waiting to be reclaimed and reburied by their families.</p>
<p class="dcr-1kas69x">History, however, has taught them not to expect too much. “Take the place in Paterna where they shot José Celda and 2,000 other people,” Terrasa said. “There’s no plaque or memorial at all like you’d find in any other civilised European country. If you go there now, you might find a bunch of now-rotten republican wreaths that were left by a memorial association, but the rest is rubbish and bottles.”</p>
<p class="dcr-1kas69x">The book ends with a picture of that refuse-strewn mass murder scene, and with a rhetorical question: “You can tell a lot about a society from the way it buries its dead. What would they say about ours?”</p>
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<br /><a href="https://www.theguardian.com/world/2024/jan/08/spanish-graphic-novel-explores-early-franco-ero-mass-burials-abyss-of-forgetting" target="_blank" rel="noopener">Source link </a></p>
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